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Pfizer vaccine: Sputnik V protects two times more against Covid than Pfizer’s vaccine: Study


Sputnik V in a statement on Thursday said that as per an independent comparative study conducted by the Spallanzani institute in Italy, its Covid-19 vaccine demonstrated strong protection against the Omicron variant of coronavirus, with over two times higher virus neutralising activity compared to the ‘s vaccine.

“A unique comparative study conducted at the Italian Spallanzani Institute, the leading Italian research institute for infectious diseases, by a joint Italian-Russian team of researchers representing the Institute and the Gamaleya Center shows that the Sputnik V coronavirus vaccine demonstrates more than 2 times higher titers of virus neutralizing antibodies to Omicron (B.1.1.529) variant than 2 doses of Pfizer vaccine (2.1 times higher in total and 2.6 times higher 3 months after vaccination),” Sputnik V said in a statement.

“Previous studies also demonstrated additional significant strengthening of protection against Omicron by Sputnik Light booster, which can also be a universal booster to other vaccines to strengthen and lengthen their protection against Omicron,” it said it its statement.

The study was conducted in equal laboratory conditions in the Spallanzani Institute in Italy on comparable sera samples from individuals vaccinated with Sputnik V and Pfizer with a similar level of IgG antibodies and virus neutralising activity (VNA) against the variant originally detected in Wuhan.

The company said that the data found in the study supports the results of the recent laboratory study by the Gamaleya Center published in MedRxiv demonstrating that Sputnik V induces robust neutralizing antibody response to Omicron variant, which is further strengthened by Sputnik Light booster.

Alexander Gintsburg, Director of the National Research Center for Epidemiology and Microbiology, said “The joint study by the Gamaleya Center and Spallanzani Institute confirmed the results obtained in our separate study published in December 2021. The hard scientific data proves Sputnik V has higher virus neutralizing activity against Omicron as compared to other vaccines and will play a major role in the global fight against this new contagious variant.”

Sputnik V said the reasons for higher vaccine performance include a wide pool of antibodies vs Pfizer’s less flexible proline-stabilized structure producing antibodies to most mutated virus part, Mix and match scheme with 2 different shots and adenoviral vectors better mimicking natural infection.


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